PSB-1434

• Description:

  PSB-1434 is a selective monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.59 nM. PSB-1434 shows >6000-fold selective for MAO-B than MAO-A[1].

• Product Name Alternative:

  1,25-Dihydroxyvitamin D3-13C12, 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3, 1,25-Dihydroxyvitamin D3-d12

• UNSPSC:

  12352005

• Target:

  Monoamine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/psb-1434.html

• Purity:

  98.05

• Solubility:

  DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(NC1=CC=C(C(F)=C1)F)C2=CC3=C(C=C2)NN=C3

• Molecular Formula:

  C14H9F2N3O

• Molecular Weight:

  273.24

• References & Citations:

  [1]Tzvetkov NT, et al., Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57 (15) :6679-703.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  MAO-B

• CAS Number:

  [1619884-65-9]