Products for Research Use Only
RegisterLogin

I-A09

CAT: 0804-HY-14988Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14988Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
I-A09 and its derivatives, specifically 1,2,3-triazole-adamantylacetamide hybrids (5a–u), exhibit significant antitubercular activity. These hybrids were synthesized using copper-catalyzed click chemistry, combining bioactive fragments from antitubercular I-A09 and substituted adamantyl urea. The compound N- (1-adamantyl) -2-azido acetamide was reacted with various alkyl/aryl acetylenes to produce new analogues. Among them, N- (1-adamantan-1-yl) -2- (4- (phenanthren-2-yl) -1H-1,2,3-triazol-1-yl) acetamide (5t) showed the most promise with a minimum inhibitory concentration (MIC) of 3.12 μg/mL against Mycobacterium tuberculosis H37Rv, and a selectivity index greater than 15[1].
CAS Number
1143579-76-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/i-a09.html
Smiles
O=C(C1=CC2=C(C=C1O)OC(C3=CC=CC=C3)=C2C4=CN(CC(NC5=CC=C(N6CCOCC6)C=C5)=O)N=N4)O
Molecular Formula
C29H25N5O6
Molecular Weight
539.54
References & Citations
[1]Design, synthesis and evaluation of 1,2,3-triazole adamantylacetamide hybrids as potent inhibitors of Mycobacterium tuberculosis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-155245-01A09-003
HY-E70040Endoglycoceramidase I (EGCase I)
HY-KE7028Not I
HY-KE8010Exonuclease I
HY-P11142Jelleine-I
HY-N5196Nocathiacin I
HY-N10917Xanthohumol I
HY-W442226PEG3-I
HY-19541-01I-CBP112
HY-N0407-01Picroside I

Alternative Products

CatalogName
MBS5775241I-A09
BUP08484-01A09-003
CS-T-20456α, α-Dimethylphenethylformamide
D0050-100Deoxyribonuclease I (DNase I)
A2299-08FApolipoprotein A-I (Apo A-I)
PT_41499-01Melanotan-I (MT I)
M41621Scyliorhinin I, Scy I
D8071-01Deoxyribonuelease I, Dnase I
GTR19220451-01Endoglycoceramidase I (EGCase I)
MBS658000-01Hymenistatin I (HS-I)

Popular Products