A09-003

• Target :

  Bcl-2 Family|||Apoptosis|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint|||Apoptosis

• Purity :

  0.9984

• Bioactivity :

  A09-003 is a novel cell cycle protein-dependent kinase-9 CDK-9 inhibitor.A09-003 inhibits the proliferation of a variety of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in myeloid cells.A09-003 also induces apoptosis, decreases RNA polymerase II activity, and decreases Mcl-1 expression.

• Smiles :

  N=1C=CC(=CC1NC2=CC=CC(=C2)N3CCNCCC3)C=4C=CC=CC4OC

• Molecular Formula :

  C23H26N4O

• Molecular Weight :

  374.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2911646-14-3