UNC3866 (TFA)
CAT:
804-HY-100832A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
UNC3866 (TFA)
- CAS Number: 1872382-48-3
- UNSPSC Description: UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
- Target Antigen: Histone Methyltransferase
- Type: Peptides
- Related Pathways: Epigenetics
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/unc3866-tfa.html
- Smiles: OC(C(F)(F)F)=O.O=C(C1=CC=C(C=C1)C(C)(C)C)N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(OC)=O)=O)=O)=O)=O)CC2=CC=CC=C2
- Molecular Weight: 909.04
- References & Citations: [1]Stuckey JI, et al. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat Chem Biol. 2016 Mar;12(3):180-7.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported