UNC3866 (TFA)

CAT: 0804-HY-100832ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100832ASize:1 Each
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Description
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
CAS Number
[1872382-48-3]
UNSPSC
12352209
Target
Histone Methyltransferase
Type
Peptides
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unc3866-tfa.html
Smiles
OC(C(F)(F)F)=O.O=C(C1=CC=C(C=C1)C(C)(C)C)N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(OC)=O)=O)=O)=O)=O)CC2=CC=CC=C2
Molecular Formula
C45H67F3N6O10
Molecular Weight
909.04
References & Citations
[1]Stuckey JI, et al. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat Chem Biol. 2016 Mar;12 (3) :180-7.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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Alternative Products

CatalogName
M23852-01UNC3866 TFA (1872382-47-2 free base)
MBS3613508-01UNC3866 TFA(1872382-47-2 free base)
526869UNC3866
A11599-25UNC3866 25mg
A11599-1UNC3866 1mg
A11599-50UNC3866 50mg
A11599-5UNC3866 5mg
A11599-10UNC3866 10mg
A11599-100UNC3866 100mg
A11599-10mM-DUNC3866 10mM * 1mL in DMSO

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