Verapamil-d7

CAT: 0804-HY-14275S1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-14275S1Size:1 mg
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Description
Verapamil-d7 is the deuterium labeled Verapamil (HY-14275) . Verapamil ((±) -Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research[1][2][3].
CAS Number
[100578-79-8]
Product Name Alternative
(±) -Verapamil-d7; CP-16533-1-d7
UNSPSC
12352005
Target
Calcium Channel; Cytochrome P450; Isotope-Labeled Compounds; P-glycoprotein
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Solubility
10 mM in DMSO
Smiles
[2H]C(C(CCCN(CCC1=CC(OC)=C(C=C1)OC)C)(C2=CC(OC)=C(C=C2)OC)C#N)(C([2H])([2H])[2H])C([2H])([2H])[2H]
Molecular Formula
C27H31D7N2O4
Molecular Weight
461.64
References & Citations
[1]Gowarty JL, et al. Verapamil as a culprit of palbociclib toxicity. J Oncol Pharm Pract. 2019 Apr;25 (3) :743-746.|[2]Krikler DM. Verapamil in arrhythmia. Br J Clin Pharmacol. 1986;21 Suppl 2:183S-189S. |[3]Rehnqvist N, et al. Effects of metoprolol vs verapamil in patients with stable angina pectoris. The Angina Prognosis Study in Stockholm (APSIS) . Eur Heart J. 1996 Jan;17 (1) :76-81.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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RM-V051827-01Verapamil-D7
MF-0102329-01Verapamil-d7 Hydrochloride
MF-0002222-01(+/-) -Verapamil hydrochloride-d7
RM-V051826-01Verapamil EP Impurity J-D7 (N-Desmethyl Verapamil-D7)
MF-0102017-01R-Verapamil-d7 HCL
460868Nor Verapamil-d7, Hydrochloride
ESS0360-01Nor Verapamil-D7 Hydrochloride
468628-01Verapamil-d7 Hydrochloride discontinued
MF-0102041-01S-Verapamil-d7 HCL
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