Antagonist G
CAT:
804-HY-P1185-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Antagonist G
- CAS Number: 115150-59-9
- UNSPSC Description: Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy[1][2].
- Target Antigen: Apoptosis; Vasopressin Receptor
- Type: Peptides
- Related Pathways: Apoptosis;GPCR/G Protein
- Applications: Cancer-programmed cell death
- Field of Research: Cancer; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/antagonist-g.html
- Purity: 99.96
- Solubility: H2O : 50 mg/mL (ultrasonic)
- Smiles: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)N(C([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCCNC(N)=N)N)=O)=O)C)=O)=O)=O
- Molecular Weight: 951.19
- References & Citations: [1]P J Woll, et al. A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro. Cancer Res. 1990 Jul 1;50(13):3968-73.|[2]A C MacKinnon, et al. [Arg6, D-Trp7,9, NmePhe8]-substance P (6–11) (antagonist G) inducesP-1 transcription and sensitizes cells to chemotherapy. Br J Cancer. 2000 Oct; 83(7): 941–948.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported