Lactoferrin (17-41)

Lactoferrin (17-41)

• CAS Number: 146897-68-9
• UNSPSC Description: Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities[1][2].
• Target Antigen: Apoptosis; Bacterial; Fungal
• Type: Peptides
• Related Pathways: Anti-infection;Apoptosis
• Applications: COVID-19-anti-virus
• Field of Research: Cancer; Infection
• Assay Protocol: https://www.medchemexpress.com/lactoferrin-17-41.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1[C@](CCC1)([H])C(N[C@H](C(N[C@@](C(N[C@@](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N2)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)NC([C@H](CCCCN)NC([C@@H](N)CC3=CC=CC=C3)=O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)([H])[C@H](O)C)=O)([H])[C@@H](C)CC)=O)CO)=O)=O)C)=O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)CCSC)=O)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)CCC(N)=O)[C@@H]2CC7=CNC8=CC=CC=C78
• Molecular Weight: 3123.77
• References & Citations: [1]Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41(2):141-8.|[2]Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells(HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95(1):99-109.|[3]Latorre D, et al. Reciprocal interactions between lactoferrin and bacterial endotoxins and their role in the regulation of the immune response. Toxins (Basel). 2010;2(1):54‐68.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported