CDK7-IN-31

• UNSPSC Description:

  CDK7-IN-31 (compound 13) is a potent and orally active cyclin-dependent kinase 7 (CDK7) inhibitor with a Kd value of 0.18 nM. CDK7-IN-31 shows anticancer activity[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk7-in-31.html

• Smiles:

  O=C(N(C)CC(CCN1C)(F)F)C2=CC=C3C(C4=NC(N[C@@H]5C[C@@H]1CC5)=NC=C4C(F)(F)F)=CNC3=C2P(C)(C)=O

• Molecular Weight:

  598.55

• References & Citations:

  [1]Lu H, et al. Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy. J Med Chem. 2024 Nov 9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2943043-62-5