CDK7-IN-31

• Target:

  Potassium Channel|||CDK

• Related Pathways:

  Cell Cycle/Checkpoint|||Membrane transporter/Ion channel

• Bioactivity:

  CDK7-IN-31 (compound 13) is an effective and orally active inhibitor of cyclin-dependent kinase 7 (CDK7) with a dissociation constant (Kd) of 0.18 nM. This compound exhibits anticancer activity.

• Smiles:

  P(C)(C)(=O)C1=C2C=3C(C4=C(C(F)(F)F)C=NC(N4)=N[C@@]5(C[C@](CC5)(N(C)CCC(F)(F)CN(C)C(=O)C1=CC3)[H])[H])=CN2

• Molecular Formula:

  C27H32F5N6O2P

• Molecular Weight:

  598.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2943043-62-5