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LY 190388

CAT: 0804-HY-P1617Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1617Size:1 Each
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Description
LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analgesic effect in inhibiting the writhing response in mice after intracerebroventricular administration. The analgesic effect of LY 190388 is not caused by its δ receptor agonist action, but by its μ receptor agonist activity. When LY 190388 is used together with the δ receptor antagonist ICI 174864, an additive analgesic effect is produced[1].
CAS Number
105496-35-3
UNSPSC
12352209
Target
Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-190388.html
Smiles
CC([C@@H](NC([C@@H](NC(CNC([C@H](NC([C@@H](N)CC1=CC=C(O)C=C1)=O)C(S)(C)C)=O)=O)CC2=CC=CC=C2)=O)C(O)=O)C
Molecular Formula
C30H41N5O7S
Molecular Weight
615.74
References & Citations
[1]Comparison of two penicillamine-containing enkephalins: mu, not delta, activity produces analgesia
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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