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TP-DEA2

CAT: 0804-HY-162929Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162929Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TP-DEA2, a predictable-release Triptolide (HY-32735) prodrug, block Bleomycin-induced pulmonary fibrosis and inflammation. TP-DEA2 significantly inhibits α-SMA production[1].
UNSPSC
12352211
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tp-dea2.html
Smiles
C[C@@]12[C@]3(O4)[C@@H]4[C@H]5[C@](C(C)C)(O5)[C@@H](OC(N(C)CCNC)=O)[C@]3(O6)[C@@H]6CC1C7=C(C(OC7)=O)CC2
Molecular Formula
C25H34N2O7
Molecular Weight
474.55
References & Citations
[1]Yuhan Chen, et al. Water-soluble and predictable-release triptolide prodrugs block bleomycin-induced pulmonary fibrosis in mice. Eur J Med Chem. 2024 Sep 6:279:116839.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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