TP-DEA2

• UNSPSC Description:

  TP-DEA2, a predictable-release Triptolide (HY-32735) prodrug, block Bleomycin-induced pulmonary fibrosis and inflammation. TP-DEA2 significantly inhibits α-SMA production[1].

• Target Antigen:

  TGF-β Receptor

• Type:

  Reference compound

• Related Pathways:

  TGF-beta/Smad

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/tp-dea2.html

• Smiles:

  C[C@@]12[C@]3(O4)[C@@H]4[C@H]5[C@](C(C)C)(O5)[C@@H](OC(N(C)CCNC)=O)[C@]3(O6)[C@@H]6CC1C7=C(C(OC7)=O)CC2

• Molecular Weight:

  474.55

• References & Citations:

  [1]Yuhan Chen, et al. Water-soluble and predictable-release triptolide prodrugs block bleomycin-induced pulmonary fibrosis in mice. Eur J Med Chem. 2024 Sep 6:279:116839.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported