TP-DEA2

• Description :

  TP-DEA2, a predictable-release Triptolide (HY-32735) prodrug, block Bleomycin-induced pulmonary fibrosis and inflammation. TP-DEA2 significantly inhibits α-SMA production[1].

• UNSPSC :

  12352211

• Target :

  TGF-β Receptor

• Type :

  Reference compound

• Related Pathways :

  TGF-beta/Smad

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/tp-dea2.html

• Smiles :

  C[C@@]12[C@]3(O4)[C@@H]4[C@H]5[C@](C(C)C)(O5)[C@@H](OC(N(C)CCNC)=O)[C@]3(O6)[C@@H]6CC1C7=C(C(OC7)=O)CC2

• Molecular Formula :

  C25H34N2O7

• Molecular Weight :

  474.55

• References & Citations :

  [1]Yuhan Chen, et al. Water-soluble and predictable-release triptolide prodrugs block bleomycin-induced pulmonary fibrosis in mice. Eur J Med Chem. 2024 Sep 6:279:116839.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported