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ALK-IN-29

CAT: 0804-HY-168513Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168513Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ALK-IN-29 (compound 4c) has a certain inhibitory effect on tyrosine protein kinases ALK, CDK2/CyclinE1 and FAK, among which the strongest inhibitory effect on ALK kinase is 40.63% at a concentration of 10 μM. ALK-IN-29 can be used for anti-cancer research[1].
UNSPSC
12352101
Target
Anaplastic lymphoma kinase (ALK) ; CDK; FAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk-in-29.html
Smiles
O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC(C4=N5)=C(C6=CC=C(F)C=C6)N7C5=CC=N7
Molecular Formula
C29H32FN3O
Molecular Weight
457.58
References & Citations
[1]Liu F, et al. Heterocycle-functional steroidal derivatives: Design, synthesis, bioevaluation and SARs of steroidal pyrazolo[1,5-a]pyrimidines as potential ALK inhibitors. Bioorg Chem. 2024 Sep 27;153:107847.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2

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