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Ginsenoside Rg2

CAT: 0804-HY-N0602-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0602-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS) . Ginsenoside Rg2 also reduces Aβ1-42 accumulation.
CAS Number
52286-74-5
Product Name Alternative
Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β; NF-κB
Type
Natural Products
Related Pathways
Neuronal Signaling; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Ginsenoside-Rg2.html
Purity
98.11
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC6)C
Molecular Formula
C42H72O13
Molecular Weight
785.01
Precautions
H302, H315, H319, H335
References & Citations
[1]Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013 Apr;17 (2) :133-7.|[2]Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40 (1) :9-17.|[3]Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013;17 (2) :133-137.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NF-κB