Ginsenoside Rg2

• Description:

  Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS) . Ginsenoside Rg2 also reduces Aβ1-42 accumulation.

• Product Name Alternative:

  Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Amyloid-β; NF-κB

• Type:

  Natural Products

• Related Pathways:

  Neuronal Signaling; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Neurological Disease; Cardiovascular Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Ginsenoside-Rg2.html

• Purity:

  98.11

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC6)C

• Molecular Formula:

  C42H72O13

• Molecular Weight:

  785.01

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013 Apr;17 (2) :133-7.|[2]Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40 (1) :9-17.|[3]Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013;17 (2) :133-137.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  NF-κB

• CAS Number:

  [52286-74-5]