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BAY 2416964

CAT: 0804-HY-135829-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135829-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment[1].
CAS Number
2242464-44-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ahr-antagonist-3.html
Purity
99.59
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CN(C)N=C3)C1=O)N[C@@H](C)CO
Molecular Formula
C18H18ClN5O3
Molecular Weight
387.82
Precautions
H302, H315, H319, H335
References & Citations
[1]Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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Alternative Products

CatalogName
bs-7082C-01BAY-2416964
BUP12022-01BAY 2416964
A22067-100BAY 2416964 100mg
A22067-5BAY 2416964 5mg
A22067-1BAY 2416964 1mg
A22067-50BAY 2416964 50mg
A22067-500BAY 2416964 500mg
A22067-25BAY 2416964 25mg
A22067-10BAY 2416964 10mg
A22067-10mM-DBAY 2416964 10mM * 1mL in DMSO

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