Microcystin-LF

Microcystin-LF

• CAS Number: 154037-70-4
• UNSPSC Description: Microcystin-LF is a bacterial metabolite. Microcystin-LF is a phenylalanine variant of Microcystin-LR. Microcystin-LF has cellular toxicity on Caco-2 cells[1][2].
• Target Antigen: Bacterial
• Type: Natural Products
• Related Pathways: Anti-infection
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@H]([C@@H](C(N[C@H](CCC(N(C1=C)C)=O)C(O)=O)=O)C)/C=C/C(C)=C/[C@H](C)[C@@H](OC)CC2=CC=CC=C2)[C@@H](NC([C@H]([C@@H](NC([C@@H](NC([C@H](NC1=O)C)=O)CC(C)C)=O)C(O)=O)C)=O)CC3=CC=CC=C3
• Molecular Weight: 986.16
• References & Citations: [1]Lawton LA, et al. Isolation and characterization of microcystins from laboratory cultures and environmental samples of Microcystis aeruginosa and from an associated animal toxicosis. Nat Toxins. 1995;3(1):50-7. |[2]Vesterkvist PS, et al. Comparative cellular toxicity of hydrophilic and hydrophobic microcystins on Caco-2 cells. Toxins (Basel). 2012 Oct 25;4(11):1008-23.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported