IN-2-LF

• Description:

  IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R[1].

• UNSPSC:

  12352209

• Target:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/in-2-lf.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1)=CC=C1C[C@H](NC(CNC(C)=O)=O)C(NCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@H](C(NO)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C81H150N42O17

• Molecular Weight:

  1984.33

• References & Citations:

  [1]Peinado JR, et al. Cross-inhibition between furin and lethal factor inhibitors. Biochem Biophys Res Commun. 2004 Aug 27;321 (3) :601-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [749879-64-9]