SEN-1269

• UNSPSC Description:

  SEN-1269 is a potent Aβ aggregation inhibitor. SEN-1269 blocks Aβ(1-42) aggregation and protects neuronal cell lines exposed to Aβ(1-42). SEN-1269 reduces the deficits in LTP and memory induced by Aβ oligomers. SEN-1269 can be used for the research of Alzheimer's disease[1].

• Target Antigen:

  Amyloid-β

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sen-1269.html

• Smiles:

  OC1=CC=CC(NC2=NC=C(OC3=CC=CC(N(C)C)=C3)C=N2)=C1

• Molecular Weight:

  322.36

• References & Citations:

  [1]Scopes DI, et al. Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity. Br J Pharmacol. 2012 Sep;167(2):383-92.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  956128-01-1