Products for Research Use Only
RegisterLogin

XL-126

CAT: 0804-HY-163271Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-163271Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
XL-126 (Compound 33) is a potent BD1-selective BET inhibitor, with a Kd of 8.9 nM. XL-126 leads to both the preservation of platelets and potent anti-inflammatory efficacy by BD1 selectivity[1].
CAS Number
3033576-12-1
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xl-126.html
Solubility
10 mM in DMSO
Smiles
O=C1C(NC2CCNCC2)=CC(C3=CC(NS(=O)(CC)=O)=C(C4=C3)C=CN4C(C)(C5=NC=CC=C5)C6=CC=CC=N6)=CN1C
Molecular Formula
C33H37N7O3S
Molecular Weight
611.76
References & Citations
[1]Li Y, et al. Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET) -First Bromodomain (BD1) Inhibitors. J Med Chem. 2024 Jan 31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-162964EGFR-IN-126
HY-161778ZG-126
HY-P0305-01PrP (106-126)
HY-P5321-01BFGF (119-126)
HY-149873-01Anticancer agent 126
HY-P1584Nucleoprotein (118-126)
HY-157317Antitumor agent-126
HY-151925Antibacterial agent 126
HY-174802-01XL-3158
HY-13787XL-418

Alternative Products

CatalogName
T209190-01XL-126
301401MAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126)
301401-PEMAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126) (PE)
301401-HRPMAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126) (HRP)
MBS6452763-01MAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126) (AP)
301401-FITCMAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126) (FITC)
MBS6452764-01MAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126) (APC)
301401-BiotinMAP126 (MAP-126, Microtubule-Associated Protein 126, MAP 126) (Biotin)
TEA40962-01AG 126
S6596-25mgAG-126

Popular Products