SEN 304

• Description:

  SEN 304 is an Aβ aggregation inhibitor. SEN 304 can bind directly to Aβ (1-42), delay β-sheet formation and promote aggregation of toxic oligomers into a nontoxic form. SEN 304 can be used for research of Alzheimer’s disease[1].

• UNSPSC:

  12352209

• Target:

  Amyloid-β

• Type:

  Peptides

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sen-304.html

• Smiles:

  N[C@H](C1CCCCC1)C(N[C@H](CC2=CC=C(O)C=C2)C(N[C@H](C3CCCCC3)C(N[C@H](C4CCCCC4)C(N(C)[C@H](CC(C)C)C(N)=O)=O)=O)=O)=O

• Molecular Formula:

  C40H64N6O6

• Molecular Weight:

  724.97

• References & Citations:

  [1]Amijee H, et al. The N-methylated peptide SEN304 powerfully inhibits Aβ (1-42) toxicity by perturbing oligomer formation. Biochemistry. 2012 Oct 23;51 (42) :8338-52.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [906357-94-6]