SEN 304

• UNSPSC Description:

  SEN 304 is an Aβ aggregation inhibitor. SEN 304 can bind directly to Aβ(1-42), delay β-sheet formation and promote aggregation of toxic oligomers into a nontoxic form. SEN 304 can be used for research of Alzheimer’s disease[1].

• Target Antigen:

  Amyloid-β

• Type:

  Peptides

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sen-304.html

• Smiles:

  O=C(O)[C@H](NC(C=C1)=CC=C1C[C@H](C(N[C@@H](C(N[C@@H](C(N(C)[C@H](CC(C)C)C(N)=O)=O)C2CCCCC2)=O)C3CCCCC3)=O)N)C4CCCCC4

• Molecular Weight:

  724.97

• References & Citations:

  [1]Amijee H, et al. The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation. Biochemistry. 2012 Oct 23;51(42):8338-52.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported