Tyk2-IN-18
CAT:
804-HY-158692
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tyk2-IN-18
- CAS Number: 3024860-29-2
- UNSPSC Description: Tyk2-IN-18 (compound 86) is a potent tyrosine kinase 2 (Tyk2) inhibitor. Tyk2-IN-18 inhibits JAK2-JH2, with an IC50 of [1][2].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tyk2-in-18.html
- Smiles: COCCOC1=CC(C(F)(F)C)=NC(N2CC3(C4=C2C=C(N=C4)NC(C)=O)CC3)=C1
- Molecular Weight: 418.44
- References & Citations: [1]Ram W. Sabnis. Novel Tyrosine Kinase 2 Inhibitors for Treating Autoimmune and Inflammatory Diseases. ACS Med. Chem. Lett. May 16, 2024.|[2]Jeffrey Vessels, et al. Tyrosine kinase 2 inhibitors and uses thereof. WO2023250064A1. 2023-12-28.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported