Products for Research Use Only
RegisterLogin

4′-Hydroxyflavone

CAT: 0804-HY-W319094-02Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W319094-02Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
4′-Hydroxyflavone (compound 50) can inhibit aldose reductase, with IC50 12 μM[1].
CAS Number
4143-63-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Assay Protocol
https://www.medchemexpress.com/4-hydroxyflavone.html
Purity
97.0
Smiles
C1=CC=C2C(=C1)C(=O)C=C(C3=CC=C(C=C3)O)O2
Molecular Formula
C15H10O3
Molecular Weight
238.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Michael Fernández, et al. Quantitative structure-activity relationship to predict differential inhibition of aldose reductase by flavonoid compounds. Bioorg Med Chem. 2005 May 2;13 (9) :3269-77.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

4'-Hydroxyflavone

structure in first source

CAS Number4143-63-9
PubChem CID229016
IUPAC Name2-(4-hydroxyphenyl)chromen-4-one
Molecular FormulaC15H10O3
Molecular Weight238.24
XLogP3.2
Topological Polar Surface Area46.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity353
SMILES
C1=CC=C2C(=C1)C(=O)C=C(O2)C3=CC=C(C=C3)O
InChI
InChI=1S/C15H10O3/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9,16H
InChIKey
SHGLJXBLXNNCTE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4'-Hydroxyflavone
CAS: 4143-63-9
CID: 229016
Formula: C15H10O3
MW: 238.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight238.24
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass238.062994177
Monoisotopic Mass238.062994177
Topological Polar Surface Area46.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity353
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-1748297,4'-Dimethoxy-3-hydroxyflavone
HY-N7108-017-Hydroxyflavone
HY-N7110-016-Hydroxyflavone
HY-22024-015-Hydroxyflavone
HY-N7108R-017-Hydroxyflavone (Standard)
HY-149469-013,7,2',4'-Tetramethoxy-5-hydroxyflavone
HY-N26645-Acetoxy-7-hydroxyflavone
HY-N8495-014'-Hydroxyflavanone
HY-W5122534-Hydroxyflavan
HY-N8495R4'-Hydroxyflavanone (Standard)

Alternative Products

CatalogName
GTR192695114'-Hydroxyflavone
M32560-014-Hydroxyflavone
GW8878-100mg4''-Diethylamino-3-hydroxyflavone
OR0975T4'-Amino-6-hydroxyflavone
OR144004'-Ethoxy-3-hydroxyflavone
MBS57520464',7-DIMETHOXY-5-HYDROXYFLAVONE
GTR19157735-014'7-DIMETHOXY-5-HYDROXYFLAVONE
VCA46018-013'-Hydroxyflavone
280094-015-Hydroxyflavone
AB08693-Hydroxyflavone

Popular Products