DM4-SMCC
CAT:
804-HY-126494-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DM4-SMCC
- CAS Number: 1228105-52-9
- UNSPSC Description: DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker[1].
- Target Antigen: Drug-Linker Conjugates for ADC
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dm4-smcc.html
- Purity: 96.86
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCC(C)(C)SC(C5)C(N(CC6CCC(C(ON7C(CCC7=O)=O)=O)CC6)C5=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
- Molecular Weight: 1114.69
- References & Citations: [1]Singh R, et al. A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved TargetedKilling of Cancer Cells. Mol Cancer Ther. 2016 Jun;15(6):1311-20.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported