Doxorubicin-SMCC

Doxorubicin-SMCC

• Product Name Alternative: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
• CAS Number: 400647-59-8
• UNSPSC Description: Doxorubicin-SMCC is a agent-linker conjugate for ADC. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/doxorubicin-smcc.html
• Purity: 98.80
• Solubility: DMSO : 62.5 mg/mL (ultrasonic)
• Smiles: C[C@@H]1O[C@H](C[C@@H]([C@@H]1O)NC(C2CCC(CC2)CN3C(C=CC3=O)=O)=O)O[C@H]4C[C@](O)(C(CO)=O)CC5=C(O)C(C(C6=C7C(OC)=CC=C6)=O)=C(C7=O)C(O)=C45
• Molecular Weight: 762.76
• References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported