JC-1

• Background :

  JC-1 is a fluorescent dye that is able to pass across the mitochondrial membrane. It is used to measure mitochondrial membrane potential. At low membrane potentials, it remains a monomer and emits green-fluorescent light (λex=485 nm, λem=520 nm). At higher membrane potentials, it forms "J-aggregates", which emit red-fluorescent light (λex=520-570 nm, λem=570-610 nm). The ratio of red/green fluorescence is based only on the membrane potential, and not on mitochondrial size, shape or density.

• Description :

  Mitochondrial membrane-potential dependent fluorescent dye

• Product Name Alternative :

  5,5,6,6-Tetrachloro-1,1,3,3-tetraethylbenzimidazolylcarbocyanine iodide, , 5,6-dichloro-2-[ (E) -3- (5,6-dichloro-1,3-diethylbenzimidazol-3-ium-2-yl) prop-2-enylidene]-1,3-diethylbenzimidazole; iodide, Jc-1; 3520-43-2; JC-1 jodide; JC1 dye; CBIC2 (3) ; 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide

• UNSPSC :

  41116105

• Type :

  Membrane Potential Probe

• Source :

  Synthetic

• Field of Research :

  Cancer | Apoptosis | Mitochondrial | Cell Cycle | Tags and Cell Markers | Fluorescent Proteins

• Purity :

  >98% (HPLC) ; NMR (Conforms)

• Weight :

  0.005

• Format :

  Red powder

• Solubility :

  May be dissolved in DMSO (20 mg/ml)

• Molecular Formula :

  C25H27Cl4IN4

• Molecular Weight :

  652.2

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• CAS Number :

  3520-43-2