JC-1

CAT: 0400-SIH-562-1MGSize: 1 mgDry Ice: NoHazardous: No
SIH-562-1MG1 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JC-1 is a fluorescent dye that is able to pass across the mitochondrial membrane. It is used to measure mitochondrial membrane potential. At low membrane potentials, it remains a monomer and emits green-fluorescent light (λex=485 nm, λem=520 nm). At higher membrane potentials, it forms "J-aggregates", which emit red-fluorescent light (λex=520-570 nm, λem=570-610 nm). The ratio of red/green fluorescence is based only on the membrane potential, and not on mitochondrial size, shape or density.
Description
Mitochondrial membrane-potential dependent fluorescent dye
CAS Number
3520-43-2
Product Name Alternative
5,5,6,6-Tetrachloro-1,1,3,3-tetraethylbenzimidazolylcarbocyanine iodide, , 5,6-dichloro-2-[ (E) -3- (5,6-dichloro-1,3-diethylbenzimidazol-3-ium-2-yl) prop-2-enylidene]-1,3-diethylbenzimidazole; iodide, Jc-1; 3520-43-2; JC-1 jodide; JC1 dye; CBIC2 (3) ; 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide
UNSPSC
41116105
Type
Membrane Potential Probe
Source
Synthetic
Field of Research
Cancer | Apoptosis | Mitochondrial | Cell Cycle | Tags and Cell Markers | Fluorescent Proteins
Purity
>98% (HPLC) ; NMR (Conforms)
Weight
0.005
Format
Red powder
Solubility
May be dissolved in DMSO (20 mg/ml)
Molecular Formula
C25H27Cl4IN4
Molecular Weight
652.2
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.