Triacsin C

• Background:

  Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism (1). It is also a potent vasodilator.

• Description:

  Acyl-CoA synthetase inhibitor

• Product Name Alternative:

  (3E) -1-Oxo-3-[ (2E,4E,7E) -2,4,7-undecatrien-1-ylidene]triazane

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  90% (HPLC) ; NMR (Conforms) .

• Weight:

  0.0001

• Format:

  Oil dissolved in DMSO (1mg/ml)

• Solubility:

  Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)

• Molecular Formula:

  C11H17N3O

• Molecular Weight:

  207.27

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1.  Igal R.A., Wang P., Coleman R.A. (1997) Biochem J. 324(Pt2): 529-534.

• CAS Number:

  76896-80-5