RNB-61

CAT: 0804-HY-163825Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-163825Size:1 Each
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Description
RNB-61 is an oral active agonist of cannabinoid CB2 receptor (CB2R), with the Ki ranging from 0.13 nM to 1.81 nM. RNB-61 has nephroprotective and/or antifibrotic effects. RNB-61 has negligible penetration into the brain[1].
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rnb-61.html
Smiles
CN1C(C(C)(C)C)=C/C(N1CC2CCC2)=N\C(C3=C(C=CC(C(F)(F)F)=C3)OCC(C)(O)C)=O
Molecular Formula
C25H34F3N3O3
Molecular Weight
481.55
References & Citations
[1]Andrea Chicca, et al. A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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