RNB-61

• UNSPSC Description:

  RNB-61 is an oral active agonist of cannabinoid CB2 receptor (CB2R), with the Ki ranging from 0.13 nM to 1.81 nM. RNB-61 has nephroprotective and/or antifibrotic effects. RNB-61 has negligible penetration into the brain[1].

• Target Antigen:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/rnb-61.html

• Smiles:

  CN1C(C(C)(C)C)=C/C(N1CC2CCC2)=N\C(C3=C(C=CC(C(F)(F)F)=C3)OCC(C)(O)C)=O

• Molecular Weight:

  481.55

• References & Citations:

  [1]Andrea Chicca, et al. A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported