RNB-61

• Description :

  RNB-61 is an oral active agonist of cannabinoid CB2 receptor (CB2R), with the Ki ranging from 0.13 nM to 1.81 nM. RNB-61 has nephroprotective and/or antifibrotic effects. RNB-61 has negligible penetration into the brain[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/rnb-61.html

• Smiles :

  CN1C(C(C)(C)C)=C/C(N1CC2CCC2)=N\C(C3=C(C=CC(C(F)(F)F)=C3)OCC(C)(O)C)=O

• Molecular Formula :

  C25H34F3N3O3

• Molecular Weight :

  481.55

• References & Citations :

  [1]Andrea Chicca, et al. A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported