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11-Dehydrocorticosterone

CAT: 0804-HY-113447-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113447-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast[1].
CAS Number
72-23-1
Product Name Alternative
SHP-141
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/11-dehydrocorticosterone.html
Purity
96.87
Solubility
DMSO : 30 mg/mL (ultrasonic)
Smiles
C[C@@]1(C2)[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O
Molecular Formula
C21H28O4
Molecular Weight
344.44
References & Citations
[1]Sheppard KE, et al. 11Beta-hydroxysteroid dehydrogenase 1 transforms 11-dehydrocorticosterone into transcriptionally active glucocorticoid in neonatal rat heart. Endocrinology. 2002;143 (1) :198-204.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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