IETD-CHO (TFA)

IETD-CHO (TFA)

• UNSPSC Description: IETD-CHO TFA (Caspase-8-IN-1) is a potent caspase-8 inhibitor[1].
• Target Antigen: Caspase
• Type: Peptides
• Related Pathways: Apoptosis
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ietd-cho-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: CC(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
• Molecular Weight: 2000.42 (free acid)
• References & Citations: [1]Joshi SG, et al. Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity. Infect Immun. 2003 Jul;71(7):4127-36.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported