Products for Research Use Only
RegisterLogin

PI3Kα-IN-9

CAT: 0804-HY-150618-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-150618-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PI3Kα-IN-9 (compound 27) is a selective, long-acting and oral active PI3Kα inhibitor with IC50 values of 4.4, 128, 146 and 153 nM for PI3Kα, PI3Kγ, PI3Kδ and PI3Kβ, respectively. PI3Kα-IN-9 has antiproliferative activity and induces apoptosis. PI3Kα-IN-9 can be used for cancer research[1].
CAS Number
2715287-67-3
UNSPSC
12352005
Target
Apoptosis; PI3K
Type
Reference compound
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kα-in-9.html
Purity
99.17
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
NC1=NC2=CC(C3=NC(N4CCOCC4)=NC(N5CCOCC5)=N3)=CC=C2O1
Molecular Formula
C18H21N7O3
Molecular Weight
383.40
References & Citations
[1]Hou Y, et, al. Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer. J Med Chem. 2022 Jul 14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

Related Products

CatalogName
HY-147285PI3K/mTOR Inhibitor-9
HY-108418-01PI3Kδ-IN-15
HY-122593-01PI3Kδ-IN-5
HY-142677PI3K-IN-27
HY-136806PI3K-IN-12
HY-160282PI3K-IN-49
HY-156080PI3K-IN-48
HY-157125PI3Kα-IN-14
HY-150034-01PI3K-IN-38
HY-160418PI3K-IN-51

Alternative Products

CatalogName
BA3043-5PI3Kα-IN-9
MBS5767334PI3K-IN-9
GTR19189384PI3Kδ-IN-9
MBS5805126PI3K/mTOR Inhibitor-9
YP-W200332-01Bovine PI3K (PI3K) ELISA Kit
YP-W63206-01Chicken PI3K (PI3K) ELISA Kit
abx236423PI3K P87 (PI3K p87) Antibody
abx037680-01Alpha (PI3K P85) (PI3K p85) Antibody
BA8725-1PI3K-IN-22
BA8769-10PI3Kδ-IN-5

Popular Products