NVS-PAK1-C

• UNSPSC Description:

  NVS-PAK1-C is a potent,?ATP-competitive and specific allosteric PAK1 inhibitor probe with IC50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC50=270 nM) and phosphorylated PAK2 (IC50=720 nM)[1].

• Target Antigen:

  PAK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nvs-pak1-c.html

• Purity:

  99.2

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1C[C@@H](NC2=NC3=CC(F)=CC=C3N(CC(F)F)C4=CC=C(Cl)C=C42)CC1)N(C)C

• Molecular Weight:

  465.90

• References & Citations:

  [1]NVS-PAK1-1 A Chemical Probe For PAK1

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2250019-95-3