NVS-PAK1-C

CAT: 0804-HY-131043-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-131043-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

NVS-PAK1-C is a potent, ATP-competitive and specific allosteric PAK1 inhibitor probe with IC50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC50=270 nM) and phosphorylated PAK2 (IC50=720 nM) [1].

CAS Number

2250019-95-3

UNSPSC

12352005

Target

PAK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nvs-pak1-c.html

Purity

99.2

Solubility

10 mM in DMSO|DMSO : ≥ 50mg/mL

Smiles

O=C(N1C[C@@H](NC2=NC3=CC(F)=CC=C3N(CC(F)F)C4=CC=C(Cl)C=C42)CC1)N(C)C

Molecular Formula

C22H23ClF3N5O

Molecular Weight

465.90

References & Citations

[1]NVS-PAK1-1 A Chemical Probe For PAK1

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PAK1; PAK2

Related Products

Catalog	Name
HY-100519-01	NVS-PAK1-1
HY-100519R	NVS-PAK1-1 (Standard)
HY-157214-01	NVS-STG2
HY-160525-01	NVS-VHL720
HY-12339	NVS-CRF38
HY-148249	NVS-MALT1
HY-111520-01	NVS-SM2
HY-160287-01	NVS MLLT-1
HY-126299-01	NVS-BPTF-1
HY-133907-01	NVS-PI3-4

Alternative Products

Catalog	Name
T35928	NVS-PAK1-C
GTR19222048	NVS PAK1 C
IWC81674-01	NVS PAK1 1
MBS3613460-01	NVS-PAK1-1
6133/5	NVS PAK1 C 5 mg

NVS-PAK1-C

Related Products

Alternative Products

Popular Products