NVS MLLT-1
CAT:
804-HY-160287-02
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NVS MLLT-1
- CAS Number: 2561471-13-2
- UNSPSC Description: NVS MLLT-1 (compound 3) is a potent and selective MLLT1 inhibitor with Kd values of 0.18 µM, 0.24 µM, and 0.22 µM for wild-type, T1 mutants, and T3 mutants, respectively[1][2].
- Target Antigen: Epigenetic Reader Domain
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/nvs-mllt-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC2=C(C=NC=C2)C=C1)NC3=CC=C4C(NC(CN5[C@H](CCC5)C)=N4)=C3
- Molecular Weight: 385.46
- References & Citations: [1]Ni X, et al. Structure and Inhibitor Binding Characterization of Oncogenic MLLT1 Mutants. ACS Chem Biol. 2021 Apr 16;16(4):571-578.|[2]Lee J, et al. The Promise and Peril of Chemical Probe Negative Controls. ACS Chem Biol. 2021 Apr 16;16(4):579-585.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported