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22-Hydroxy Mifepristone-d6

CAT: 0804-HY-131543SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131543SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
22-Hydroxy Mifepristone-d6 is the deuterium labeled 22-Hydroxy Mifepristone. 22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human glucocorticoid receptor is 48%[1][2].
Product Name Alternative
RU 42698-d6
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
O=C1C=C2C(CC1)=C3[C@@H](C4=CC=C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C4)C[C@@]5(C)[C@@]([C@]3(C)CC2)(C)CC[C@]5(C#CCO)O
Molecular Formula
C31H33D6NO3
Molecular Weight
479.68
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported