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22-Hydroxy mifepristone

CAT: 0804-HY-131543Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131543Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human glucocorticoid receptor is 48%[1][2].
CAS Number
105012-15-5
Product Name Alternative
RU 42698
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/22-hydroxy-mifepristone.html
Smiles
O=C1C=C2C(CC1)=C3[C@@H](C4=CC=C(N(C)C)C=C4)C[C@@]5(C)[C@@]([C@]3(C)CC2)(C)CC[C@]5(C#CCO)O
Molecular Formula
C31H39NO3
Molecular Weight
473.65
Precautions
P261-P280-P302+P352
References & Citations
[1]Lähteenmäki P, et al. Pharmacokinetics and metabolism of RU 486. J Steroid Biochem. 1987;27 (4-6) :859-63.|[2]Heikinheimo O, et al. Plasma concentrations and receptor binding of RU 486 and its metabolites in humans. J Steroid Biochem. 1987 Feb;26 (2) :279-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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