Hydroxy Itraconazole-d6

• Description:

  Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

• Product Name Alternative:

  R-63373-d6

• UNSPSC:

  12352005

• Target:

  Fungal; Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Smiles:

  O=C1N (C (C ([2H]) (C ([2H]) ([2H]) [2H]) O) ([2H]) C) N=C ([2H]) N1C2=CC=C (N3CCN (CC3) C4=CC=C (C=C4) OCC5OC (C6=CC=C (C=C6Cl) Cl) (CN7N=CN=C7) OC5) C=C2

• Molecular Formula:

  C35H32D6Cl2N8O5

• Molecular Weight:

  727.67

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported