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Chlorhexidine (Standard)

CAT: 0804-HY-B1248R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1248R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chlorhexidine (Standard) is the analytical standard of Chlorhexidine. This product is intended for research and analytical applications. Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis)[2][3].
CAS Number
55-56-1
UNSPSC
12352005
Hazard Statement
H315, H319, H334, H335, H410
Target
Antibiotic; Apoptosis; Bacterial; Necroptosis; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chlorhexidine-standard.html
Purity
98.96
Smiles
N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N
Molecular Formula
C22H30Cl2N10
Molecular Weight
505.45
Precautions
H315, H319, H334, H335, H410
References & Citations
[1]Faria G, et al. Evaluation of chlorhexidine toxicity injected in the paw of mice and added to cultured l929 fibroblasts. J Endod. 2007 Jun;33 (6) :715-22.|[2]Zhang J, et al. Pulmonary Toxicity Assessment after a Single Intratracheal Inhalation of Chlorhexidine Aerosol in Mice. Toxics. 2023 Nov 7;11 (11) :910.|[3]Sanchez IR, et al. Chlorhexidine diacetate and povidone-iodine cytotoxicity to canine embryonic fibroblasts and Staphylococcus aureus. Vet Surg. 1988;17 (4) :182-185.|[4]Ribeiro DA, et al. Chlorhexidine induces DNA damage in rat peripheral leukocytes and oral mucosal cells. J Periodontal Res. 2004 Oct;39 (5) :358-61.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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