Chlorhexidine

Chlorhexidine

• CAS Number: 55-56-1
• UNSPSC Description: Chlorhexidine is an antibacterial used as an antiseptic and for other applications. Chlorhexidine is used to clean the skin after an injury, before surgery, or before an injection. Chlorhexidine is also used to clean the hands before a procedure[1].
• Target Antigen: Antibiotic; Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/Chlorhexidine.html
• Purity: 99.89
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N
• Molecular Weight: 505.45
• References & Citations: [1]Wael E Shams, et al. Peritoneal Lavage Using Chlorhexidine Gluconate at the End of Colon Surgery Reduces Postoperative Intra-Abdominal Infection in Mice. J Surg Res. 2015 May 1;195(1):121-7.|[2]Yi-Ching Li, et al. Assessment of the cytotoxicity of chlorhexidine by employing an in vitro mammalian test system. Journal of Dental Sciences. Volume 9, Issue 2, June 2014, Pages 130-135.|[3]Hon-Yeung Cheung, et al. Differential actions of chlorhexidine on the cell wall of Bacillus subtilis and Escherichia coli. PLoS One. 2012;7(5):e36659.bioRxiv. 2024 Nov 06.|Cell Death Dis. 2022 Apr 22;13(4):396.|Cell Signal. 2021 Apr 3;110002.|Front Cell Dev Biol. 30 March 2021.|Genes (Basel). 2021, 12(4), 537.|J Funct Foods. 2024 Jun.|Mol Oncol. 2020 Feb;14(2):373-386. |Nat Commun. 2021 Mar 29;12(1):1940.|Transl Oncol. 2024 Apr 24:45:101958.|Antioxidants (Basel). 2024 May 29;13(6):667.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: Launched