Alloc-DOX

Alloc-DOX

• CAS Number: 561022-65-9
• UNSPSC Description: Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth[1][2].
• Target Antigen: AMPK; Antibiotic; Apoptosis; Autophagy; Bacterial; HBV; HIV; Mitophagy; Topoisomerase
• Type: Reference compound
• Related Pathways: Anti-infection;Apoptosis;Autophagy;Cell Cycle/DNA Damage;Epigenetics;PI3K/Akt/mTOR
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/alloc-dox.html
• Smiles: OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC=C)=O
• Molecular Weight: 627.59
• References & Citations: [1]Miller MA, et al. Nano-palladium is a cellular catalyst for in vivo chemistry. Nat Commun. 2017 Jul 12;8:15906. |[2]Chen Z, et al. Bioorthogonal catalytic patch. Nat Nanotechnol. 2021 Aug;16(8):933-941.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported