Alloc-DOX

CAT: 0804-HY-158329-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-158329-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth[1][2].
CAS Number
[561022-65-9]
Product Name Alternative
N-Alloc doxorubicin
UNSPSC
12352005
Target
AMPK; Antibiotic; Apoptosis; Autophagy; Bacterial; HBV; HIV; Mitophagy; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alloc-dox.html
Purity
98.40
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC=C)=O
Molecular Formula
C31H33NO13
Molecular Weight
627.59
References & Citations
[1]Miller MA, et al. Nano-palladium is a cellular catalyst for in vivo chemistry. Nat Commun. 2017 Jul 12;8:15906. |[2]Chen Z, et al. Bioorthogonal catalytic patch. Nat Nanotechnol. 2021 Aug;16 (8) :933-941.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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