Products for Research Use Only
RegisterLogin

P-ESBP-DOX

CAT: 0804-HY-P10770Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P10770Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
P-ESBP-DOX is a HPMA copolymer-drug conjugate, which is consistituted of the E-selectin binding peptide and the Doxorubicin. P-ESBP-DOX exhibits cytotoxicity against TNFα-activated human vascular endothelial cells IVECs with an IC50 of 0.28 μM. P-ESBP-DOX can be used in research about tumor vasculature[1].
UNSPSC
12352209
Target
E-Selectin ; Peptide-Drug Conjugates (PDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/p-esbp-dox.html
Smiles
O=C(CNC(CNC(C(CC)(CC(CC(C)(C(NCC(NCC(N[C@@H](CS)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)(C(NCC(C)O)=O)C)C)=O)=O)N/N=C([C@@](O)(C[C@@H]5O[C@@H]6O[C@H]([C@H]([C@H](C6)N)O)C)CC7=C5C(O)=C8C(C9=C(OC)C=CC=C9C(C8=C7O)=O)=O)\CO.[x].[y].[z]
Molecular Weight
29120 (Average)
References & Citations
[1]Shamay Y, et al., E-selectin binding peptide-polymer-drug conjugates and their selective cytotoxicity against vascular endothelial cells. Biomaterials. 2009 Nov;30 (32) :6460-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-172491DSPE-PEG2000-ESBP
HY-172492DSPE-PEG5000-ESBP
HY-172491ADSPE-PEG3400-ESBP
HY-172490DSPE-PEG1000-ESBP
HY-158329-01Alloc-DOX
HY-153797Dox-btn2
HY-176869EMC-AANL-DOX
HY-D2437DOX-PEG-Cy3
HY-172191Czapek dox agar
HY-P10760PhAc-ALGP-Dox

Alternative Products

CatalogName
TP2991-01P-ESBP-DOX
TCL-01151-01DSPE-PEG1000-ESBP
TCL-01127-01DSPE-PEG5000-ESBP
TCL-01173-01DSPE-PEG2000-ESBP
TCL-01330-01DSPE-PEG3400-ESBP
BA1172-5Alloc-DOX
BA1090-1Dox-btn2
29212-1Czapek - Dox Agar
30620111-2Czapek Dox Agar
MBS5776918DOX-NOP1 HCl

Popular Products