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Topo IIIα Polyclonal Antibody

CAT: 0749-ABP57358-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57358-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TOP3A (topoisomerase (DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
Rabbit Anti-Topo IIIα Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
Gene ID
7156
Accession Number
Q13472
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Topo IIIα at AA range: 350-430
Clonality
Polyclonal
Tag
DNA topoisomerase 3-alpha
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
115kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
Observed Molecular Weight
115
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13472
Isotype
Rabbit IgG

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