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Topo I Polyclonal Antibody

CAT: 0749-ABP56413-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56413-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Description
Rabbit Anti-Topo I Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TOP1; DNA topoisomerase 1; DNA topoisomerase I
Gene ID
7150
Accession Number
P11387
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Topo I
Clonality
Polyclonal
Tag
DNA topoisomerase 1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
90kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Topo I Polyclonal Antibody detects endogenous levels of Topo I protein.
Observed Molecular Weight
90
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
TOP1; DNA topoisomerase 1; DNA topoisomerase I
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P11387
Isotype
Rabbit IgG

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