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OPSG rabbit pAb

CAT: 0855-ES11688-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11688-02Size:100 µL
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Background
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]
Description
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009],
UniProt
P04001
Swiss Prot
P04001
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 200-280
Target
OPSG
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein .
Gene ID (Human)
2652

UniProtKB · P04001

Medium-wave-sensitive opsin 1

OPSG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04001
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
OPN1MW
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Cellular component

Cell membraneCell projectionMembrane

Ligand

Chromophore

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

G protein-coupled receptorPhotoreceptor proteinReceptorRetinal proteinTransducer

Biological process

Sensory transductionVision

Domain

TransmembraneTransmembrane helix

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