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AMGO1 rabbit pAb

CAT: 0855-ES11320-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11320-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain., similarity:Belongs to the immunoglobulin superfamily. AMIGO family., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 6 LRR (leucine-rich) repeats., subcellular location:Associated with axons of neuronal cells., subunit:Binds itself as well as AMIGO2 and AMIGO3.
Description
Function: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. similarity: Belongs to the immunoglobulin superfamily. AMIGO family. similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. similarity: Contains 6 LRR (leucine-rich) repeats. subcellular location: Associated with axons of neuronal cells. subunit: Binds itself as well as AMIGO2 and AMIGO3.
UniProt
Q86WK6
Swiss Prot
Q86WK6
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
54kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
54kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, axon . Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal and cortical neurons. Associated with axons of neuronal cells. .
Gene ID (Human)
57463

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