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DSCAM rabbit pAb

CAT: 0855-ES11032-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11032-02Size:100 µL
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Background
This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD) . A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
Description
This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012],
UniProt
O60469
Swiss Prot
O60469
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
221kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
221kD
Fragment
IgG
Subcellular Location
[Isoform Short]: Secreted .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Cell projection, growth cone . Cell junction, synapse . Localized in the soma, cell membrane, axon and growth cone of dissociated commissural axons. .
Gene ID (Human)
1826

UniProtKB · O60469

Cell adhesion molecule DSCAM

DSCAM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60469
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DSCAM
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
O60468
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionNeurogenesis

Cellular component

Cell membraneCell projectionMembraneSecretedSynapse

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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