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DNER rabbit pAb

CAT: 0855-ES11005-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11005-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis., similarity:Contains 1 follistatin-like domain., similarity:Contains 10 EGF-like domains., subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region., subunit:Interacts with AP1G1. Interacts with NOTCH1., tissue specificity:Expressed in brain, spinal cord and adrenal gland.
Description
Function: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. similarity: Contains 1 follistatin-like domain. similarity: Contains 10 EGF-like domains. subcellular location: Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region. subunit: Interacts with AP1G1. Interacts with NOTCH1. tissue specificity: Expressed in brain, spinal cord and adrenal gland.
UniProt
Q8NFT8
Swiss Prot
Q8NFT8
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
81kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
81kD
Fragment
IgG
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity) . .
Gene ID (Human)
92737

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