DNER rabbit pAb

• Background:

  Function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis., similarity:Contains 1 follistatin-like domain., similarity:Contains 10 EGF-like domains., subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region., subunit:Interacts with AP1G1. Interacts with NOTCH1., tissue specificity:Expressed in brain, spinal cord and adrenal gland.

• Description:

  Function: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. similarity: Contains 1 follistatin-like domain. similarity: Contains 10 EGF-like domains. subcellular location: Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region. subunit: Interacts with AP1G1. Interacts with NOTCH1. tissue specificity: Expressed in brain, spinal cord and adrenal gland.

• UniProt:

  Q8NFT8

• Swiss Prot:

  Q8NFT8

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  81kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  81kD

• Fragment:

  IgG

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity) . .

• Gene ID (Human):

  92737