MK-1903

• Description:

  MK-1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  GPR109A

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/mk-1903.html

• Purity:

  99.68

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  OC(C1=NNC2=C1C[C@]3([H])[C@@]2([H])C3)=O

• Molecular Formula:

  C8H8N2O2

• Molecular Weight:

  164.16

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Boatman PD, et al. (1aR,5aR) 1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903) : a potent GPR109a agonist that lowers free fatty acids in humans. J Med Chem. 2012 Apr 26;55 (8) :3644-66.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [1268882-43-4]