RegisterLogin

UVRAG rabbit pAb

CAT: 0855-ES10871-01Size: 50 µLDry Ice: NoHazardous: No
CAT#: ES10871-01Size: 50 µL
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI (3) KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
Description
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI (3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008],
UniProt
Q9P2Y5
Swiss Prot
Q9P2Y5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein. AA range 655-675
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
76kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
76kD
Fragment
IgG
Subcellular Location
Late endosome . Lysosome . Cytoplasmic vesicle, autophagosome . Early endosome . Endoplasmic reticulum . Midbody . Chromosome, centromere . Colocalizes with RAB9-positive compartments involved in retrograde transport from late endosomes to trans-Golgi network. Colocalization with early endosomes is only partial (PubMed:24056303) . Recruited to autophagosome following interaction with RUBCNL/PACER (PubMed:28306502) . .
Gene ID (Human)
7405

Related Products

CatalogName
ES4666-01RAB3IP rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20596-01WIPI2 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb
ES20831-01ATG13 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb

Alternative Products

CatalogName
E45R28249NUVRAG Rabbit pAb
E45R28249N-50UVRAG Rabbit pAb
E45R28249N-100UVRAG Rabbit pAb
A8462-01UVRAG Rabbit pAb
E2508462UVRAG Rabbit pAb
C05763-01UVRAG Rabbit mAb
E47R9923UVRAG Rabbit pAb
MBS8547450-01UVRAG Rabbit pAb
E2370289UVRAG Rabbit pAb
MBS8536750-01UVRAG

Popular Products