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ZFHX4 rabbit pAb

CAT: 0855-ES10485-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10485-01Size:50 µL
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Background
Disease:A chromosomal aberration involving [ZFHX4] is found in one patient with ptosis. Translocation t (1;8) (p34.3; q21.12) ., function:May play a role in neural and muscle differentiation (By similarity) . May be involved in transcriptional regulation., similarity:Belongs to the krueppel C2H2-type zinc-finger protein family., similarity:Contains 20 C2H2-type zinc fingers., similarity:Contains 4 homeobox DNA-binding domains., tissue specificity:Expressed in brain, skeletal muscle and liver. Very low expression in stomach.
Description
Disease: A chromosomal aberration involving [ZFHX4] is found in one patient with ptosis. Translocation t (1;8) (p34. 3;q21. 12). function: May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation. similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. similarity: Contains 20 C2H2-type zinc fingers. similarity: Contains 4 homeobox DNA-binding domains. tissue specificity: Expressed in brain, skeletal muscle and liver. Very low expression in stomach.
UniProt
Q86UP3
Swiss Prot
Q86UP3
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
ZFHX4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF
Concentration
1 mg/ml
Dilution
WB: 1:500-1000 IHC: 1:200-500
Buffer
-20°C/1 year
Molecular Weight
392kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
392kD
Fragment
IgG
Subcellular Location
Nucleus .
Gene ID (Human)
79776

UniProtKB · Q86UP3

Zinc finger homeobox protein 4

ZFHX4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86UP3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ZFHX4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
G3V138, Q18PS0, Q6ZN20
Protein keywords

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Domain

Coiled coilHomeoboxRepeatZinc-finger

Molecular function

DNA-bindingRepressor

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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