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PURA rabbit pAb

CAT: 0855-ES10384-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10384-01Size:50 µL
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Background
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]
Description
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008],
UniProt
Q00577
Swiss Prot
Q00577
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
PURA
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Nucleus.
Gene ID (Human)
5813

UniProtKB · Q00577

Transcriptional activator protein Pur-alpha

PURA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q00577
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PURA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

ActivatorDNA-binding

Disease

Disease variantIntellectual disability

Cellular component

Nucleus

Domain

Repeat

Biological process

TranscriptionTranscription regulation

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A9296PURA Rabbit pAb
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GB115226Anti-PURA Rabbit pAb
SL19685R-01Rabbit Anti-PURA antibody
NBP1-82400Rabbit Polyclonal PURA Antibody
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